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Table 5 Demographic and clinical predictors for development of MDR in ICU cancer patients (n = 497)—bivariate analysis

From: Prevalence and determinants of antimicrobial resistance of pathogens isolated from cancer patients in an intensive care unit in Alexandria, Egypt

Patient comorbidities

MDR

Odds ratio

Confidence interval

p- value

Lower

Upper

Age exceeding 60 years

 Yes (n = 362)

186 (51.4%)

1.1

.72

1.59

0.728

 No (n = 135)

67 (49.6%)

Charlson Comorbidity Index score

 Mild & Moderate (n = 61)

37 (60.6%)

.643

.372

1.111

.111

 Severe (n = 436)

217(49.7%)

 Duration of hospitalization*, (mean ± SD) days

253 (14.4 ± 11.07)

1.05

1.02

1.07

 < .001*

Antibiotics use within 3 months *

 Yes (n = 245)

143 (58.4%)

1.8

1.25

2.5

 < .001*

 N0 (n = 252)

110 (43.7%)

Corticosteroids within 3 months

 Yes (n = 83)

48 (57.8%)

1.4

0.87

2.25

.167

 N0 (n = 414)

205 (49.5%)

Neutropenic *

 Yes (n = 71)

51 (71.8%)

2.8

1.63

4.9

 < .001*

 N0 (n = 426)

202 (47.4%)

Chemotherapy *

 Yes (n = 253)

145 (57.3%)

1.7

1.19

2.41

 < .001*

 No (n = 244)

108 (44.3%)

 Radiotherapy

 Yes (n = 88)

41 (46.6%)

0.8

0.51

1.29

0.372

 No (n = 409)

212 (51.8%)

Metastasis *

 Yes (n = 188)

120 (63.8%)

2.4

1.64

3.47

 < .001*

 No (n = 309)

132 (42.7%)

  1. *Statistically significant