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Table 1 Role of vitamin C in the modulation of several complications [69]

From: The protective role of vitamin C in the management of COVID-19: A Review

Complications Role of vitamin C
Cytokine storms A large dose of vitamin C could prevent and manage cytokine storms
Inflammatory response syndrome Vitamin C assists in regulating inflammatory response to prevent immune cell damage
Oxidative stress Prevention and management of oxidative stress through a large dose of vitamin C administration
Acute respiratory distress syndrome Vitamin C elevates ACE2 regulation and modulates the renin-angiotensin system to restore proper lung function
Hyperactivation of the other immune system responses Vitamin C helps the immune system to fight against infection
Sepsis Intravenous vitamin C administration reduces the SOFA scores and levels of pro-inflammatory markers significantly